Molecular Prognostic Factors and Pathogenesis of Endometrial Cancer
Míčková I.1, Pilka R.2, Ľubušký M.2, Kudela M.2
1Ústav lékařské genetiky a fetální medicíny, LF UP a FN, Olomouc, přednosta prof. MUDr. J. Šantavý, CSc. 2Gynekologicko-porodnická klinika, LF UP a FN, Olomouc, přednosta prof. MUDr. M. Kudela, CSc. |
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Summary:
Objective: To evaluate the importance of molecular markers for prognosis and pathogenesis of endometrial
carcinoma.
Design: A review article.
Setting: Department of Medical Genetics and Fetal Medicine, University Hospital, Olomouc, Department
of Obstetrics and Gynecology, University Hospital, Olomouc.
Methods: This article reviews the current knowledge of the molecular changes in the development of
endometrial cancer, and their possible importance for the patient’s prognosis.
Conclusion: The new molecular biomarkers are apparently going to play a significant role in the management
of endometrial carcinoma treatment in the near future.
Key words:
carcinoma, endometrium, marker, prognosis
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