The authors compared intervention strategy (vaccination) and non-intervention strategy (no vac- cination). For the evaluation of health and financial effectiveness of regular polio vaccination the authors used the modelling of treatment of polio cases in 1957, and vaccination costs in 1996 – the most recent year with available statistical data from the Slovak Republic. From these model years they calculated: the cost saving (11 919 106 Sk), cost-effectiveness ratio (79 944 Sk) and the net cost of vaccination (3 047 786 Sk). Simultaneously, they present a breakdown of cost-benefit analysis.

        Key words: polio vaccination – cost saving – cost-effectiveness – cost-benefit.