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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Vnitř. Lék., 48, 2002, No. 6, p. 529-533 |
Atherosclerosis, Alcohol, and Diabetes Bartoš V. Centrum diabetologie Institutu klinické a experimentální medicíny, Praha, přdnostka prof. MUDr. T. Pelikánová, DrSc. |
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Summary: Diabetes is a known risk factor of atherosclerosis, moderate consumption of alcohol was reported
to reduce the cardiovascular morbidity and mortality. This review presents information on the
possible mechanisms of the antiatherogenic effect of alcohol and data of the effect of moderate
alcohol drinking on the prevention of cardiovascular diseases. Red wine contains polyphenols
with an antioxidant effect, alcohol is metabolized to acetaldehyde which was proved to inhibit the
formation of advanced glycation endproducts (AGE) and lipoprotein oxidation. Diabetic patients
may benefit from moderate consumption of alcohol beverages only if the risk of hypoglycemia is
safely excluded.
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