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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
| Journals - Article | |
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| Česky / Czech version | Epidemiol. Mikrobiol. Imunol., 53, 2004, č. 2, s. 74–77 |
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Multilocus Sequence
Typing of Haemophilus influenzae Strains Křížová P.1, Kalmusová J.1, Lebedová V.1, Felsberg J.2, Haugvicová R.2 1Centrum epidemiologie a mikrobiologie, Státní zdravotní ústav, Praha2Mikrobiologický ústav AV ČR, Praha |
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Summary: First results of multilocus sequence typing (MLST) of Haemophilus influenzae strains are presented.
MLST of 28 H. influenzae strains isolated frompatients with invasive diseases in the Czech Republic
is indicative of clonal homogeneity of these strains: 22 out of 26 H. influenzae b strains tested were
of the same sequence type, ST-6. Four strains were of two sequence types newly described in this
study: ST-83 (3 strains) and ST-84 (1 strain). Two nontypeable H. influenzae strains were assigned to
sequence types other than ST-6: ST-3 and ST-85 newly described in this study. First MLST results
show ST-6 to be typical of H. influenzae b isolated from patients with invasive diseases in the Czech
Republic. The sequence types newly described in this study, i.e. ST-83, ST-84 and ST-85, were
submitted to the worldwide H. influenzae MLST database (http://haemophilus.mlst.net).
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