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  Česky / Czech version Čes. Radiol., 2005, roč. 59, č. 5, s. 264–268.
 
Evaluation of Significance in Operation Radicalism and Age for the Length of Survival Period in Patients with High Grade Glioma 
Ryška P.1, Žižka J.1, Málek V.2, Hobza V.2, Odrážka K3. , Řehák S.2, Klzo L.1,Michl A.1, Ungermann L.1 

Radiologická klinika LF a FN, Hradec Králové1 přednosta prof. MUDr. P. Eliáš, CSc. Neurochirurgická klinika FN, Hradec Králové2 přednosta doc. MUDr. J. Náhlovský, CSc. Klinika radioterapie a onkologie FN, Hradec Králové3 přednosta doc. MUDr. J. Petera, Ph.D.
 


Summary:

       Aim: The aim of this paper is to evaluate the significance of operation radicalism for the length of survival period in patients after neurosurgery of high grade glioma of brain. Materials and methods: From January 1997 to November 2003 there were 34 patients (22 males, 12 females) with high grade gliomas examined. The pre-operative and postoperative MR examinations were performed in all these patients. Results: Statistics of our group of patients proved that radical operation (>98%) significantly prolongs the survival period in comparison with patients with lower radicalism of operation (p <0.001). The age of patient and histologic tumor grading were also significant factors for the length of survival period. The volume of residual tumor (p = 0.079) was on boundary of statistical significance. Conclusions: Histologic type of the tumor, operation radicalism and age of the patient are important for the length of survival period in patients with high grade glioma (p <0.001).

        Key words: high grade gliomas – operation radicality – MRI – early postoperative controls
       

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