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  Česky / Czech version Čes. a slov. Neurol. Neurochir., 64/97, 2001, No. 2, p. 109–113.
 
Effect of Dopaminergic Stimulation in Parkinson’s Disease on Declarative and Non-declarative Memory  
Línek V., Roth J., Jech R., Volfová M., Růžička E. 

Neurologická klinika a Centrum extrapyramidových onemocnění, 1. LF UK a VFN, Praha
 


Summary:

       Ten patients with Parkinson’s disease were examined using a procedural learning task and Sternberg’s declarative short term memory test, under two condition’s: on dopaminergic medication producing an optimal motor state, and without medication. The performance in the non-declarative task was improved, while reaction times in the declarative memory test were delayed in medicated subjects. The findings lead to the conclusion that dopaminergic medication can impair declarative short-term memory even in doses producing motor improvement.

        Key words: Parkinson’s disease, declarative short-term memory, procedural learning, dopamine, dopa- minergic medication
       

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