Many patients suffering from intensive neuropathic pain cannot find adequate treatment neither in GP office nor in hospital. Tricyclic antidepres- sants, antiseizures, antiarrhythmics and other usual drugs haven’t any considered effect or this effect become very late. Nevertheless there is one very potent drug, which can offer the relief from the neuropathic pain in some seconds and provide this analgesia until definitive resolution of this problem is obtained. This drug is ketamine.

        Key words: neuropathic pain - acute pain - NMDA receptors - ketamine