In an open clinical, endoscopy controlled study involving 31 patients with erosive NSAIDs-indu- ced gastropathy without Helicobacter pylori infection, the effect of low dose of antacids (120 mmol/l) with aluminium oxide and magnesium oxide (Maalox ® ) administered for 4 weeks was followed. The administration of NSAIDs was not interrupted during the time of treatment. Hea- ling rate of the gastric erosions after four weeks reached 65 % (20/31) and endoscopic score in the gastric mucosa proved significant improvement (0,97 ± 0,49 compared to 0,07 ± 0,25, p < 0,01). Our results suggest efficacy of low dose antacids containing aluminium in the treatment of NSA- IDs-induced gastric erosions.

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