Transpupillary Thermotherapy in the Treatment of Choroidal New Vessels in
Age-Related Macular Degeneration – One Year’s Results
Studnička J., Rencová E., Korda V., Hejcmanová D., Dusová J., Kvasnička J.
Oční klinika LF UK a FN, Hradec Králové, přednosta prof. MUDr. Pavel Rozsíval, CSc. |
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Summary:
The aim of the study: Authors refer to one year’s results of the study of 56 eyes
of 50 patients with the exsudative form of the age-related macular
degeneration treated by means of transpupillary thermotherapy at the
Department of Ophthalmology, School of Medicine, Charles University, Hradec
Králové (Königgrätz), Czech Republic, EU.
Patients and methods: In all patients, the best-corrected visual acuity (BCVA)
before treatment was established. Beside the ordinary examination methods,
the digital color photography of the fundus with topography of the lesion,
fluoresceine angiography (FAG), or possibly indocyanine green angiography
and optical coherence tomography (OCT) were performed. After the treatment,
in given intervals, the BCVA was established, and retinal findings were
evaluated by means of biomicroscopic examination, comparative color
photography of the fundus, optical coherence tomography, fluoresceine
angiography, or possibly indocyanine green angiography.
Results: During one year after the treatment, the visual acuity decreased by
2 or more lines on Snellen optotypes in 38.2 % of patients, remained stable in
52.9 %, and improved in 8.8 % of patients. The FAG findings improved in 83.9 %
and the OCT findings in 84.8 % of patients. This improvement was statistically
significant. In patients with classical choroidal membrane, the BCVA
decreased in 35.8 %, remained stable in 57.1 % and improved in 7.1 % of patients.
The FAG finding improved in 78.7 %, and the OCT finding improved in 90.8 % of
patients. The improvement of the OCT findings was statistically significant. In
patients with occult choroidal membrane, the visual acuity decreased in 45 %,
remained stable in 45 %, and improved in 10 % of patients. The FAG findings
improved in 88.9 %, and the OCT findings in 78.9 % of patients. The
improvement was statistically significant.
Conclusion: Our results show that transpupillary themotherapy belongs to
important methods of treatment of the classical and occult membranes of the
choroid in exsudative forms of the ARMD.
Key words:
age-related macular degeneration, new vessels of the choroid,
transpupillary thermotherapy
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