Our communication demonstrates the feasibility of ultrasound peroperative monitoring in real-time 2D imaging during surgeries for malignant brain tumours. Twenty-five patients were evaluated, who had surgery from June 2001 to April 2002 at Clinic of Neurosurgery for the diagnosis of glioblastoma multiforme. During resection, the radicality of the surgery was verified with the help of a surgical microscope and ultrasound examination in 2D mode. Thanks to ultrasound monitoring, the radicality of the surgery was extended in 9 patients without worsening the preoperative state of the patients. Control CT,MRI and ultrasound examination were performed within 48 hours after surgery.The results of these examinations were compared to the peroperative findings in the microscopic and ultrasound images. In 21 patients, there was agreement of peroperative and postoperative findings regarding the radicality of the surgery. In 2 patients, the comparison could not be made because of an unsatisfactory temporal window during the ultrasound exam. In other two patients, postoperative bleeding at the resection site was demonstrated with an ultrasound and CT exam, therefore, the peroperative and postoperative findings could not be compared.This first experience seems to indicate that peroperative 2D ultrasound examination can significantly contribute to a safe maximal resection of brain tumours. Key words: glioblastoma, surgery, peroperative ultrasound monitoring, safe radical resection

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