We determined findings on optical coherence tomography (OCT) in macular degeneration with predominantly classic subfoveal choroidal neovascularization treated by photodynamic therapy (PDT) with Visudyne. We performed 21correlations of central retinal thickness (CRT) on OCT2 with findings on fluorescein angiography (FA) in our study.We quantifiedCRTonOCT2 in 14 cases before, during and after the end of the treatment. The control group was composed from patients, who were not able to undergo the treatment and therefore it was postponed. CRT on OCT correlated with FA in 95 % of cases in our study. Maximal decrease of CRT is demonstrated during the first three months of treatment. Values of CRT on OCT are in patients after repeated sessions of PDT lower than before the first session. These values can grow up a little for some time due to increase of amount of intraretinal fluid during the first week after the session of PDT. During next follow-up there are no big differences between values of CRT. In the control group CRT on OCT increases progressively during the follow-up.

        Key words: macular degeneration, photodynamic therapy, fluorescein angiography, optical coherence tomography