The authors will submit in their series of contributions under the common title of „Health and Economic Benefits of Compulsory Regular Vaccination in the Slovak Republic“ estimates of benefits and effectiveness of particular vaccinations. In their first contribution they deal with the objectives and methods of this evaluation essential for the allocation of funds for the maintenance of existing preventive programmes and also for the implementation of new preventive measures. On the basis of literary data and their own experience they formulate modified methods of cost/effectiveness and cost/benefit and other parameters adjusted for the conditions of the vaccination programme in the Slovak Republic.

        Key words: regular vaccination – cost/effectiveness – cost/benefit.