CzMA JEP Home page CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ
Journals - Article
CzMA JEP Home page News About Assocation Publishing Division Medical Journals Searching Supplements Catalogue
 
  Česky / Czech version Čes. slov. Farm. 52, 2003, No. 6, p. 291–294
 
A Novel Group of Potential Antituberculotic Agents: Antimycobacterial N-Benzylsalicylamides 
WAISSER K., PEŘINA M., BOUDOVÁ I., KUNEŠ J., KAUSTOVÁ J.1 

Katedra anorganické a organické chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové1 Oddělení pro diagnostiku mykobakterií – Krajská hygienická stanice, Ostrava
 


Summary:

       Linking up with a previous study of antimycobacterial compounds, several groups of N-benzylsalicylamides were prepared and their antimycobacterial activities against the strains Mycobacterium tuberculosis,Mycobacterium kansasii, and Mycobacterium aviumwere evaluated.The obtained data were analyzed by Free-Wilson method in comparison with their isosteric analogues of 3-hydroxypicolinic and 2-sulfanylbenzoic acids described in the previous communication.

        Key words: N-benzylsalicylamides – mycobacterium – tuberculostatics – QSAR
       

Order this issue

  BACK TO CONTENTS  
 
 
| HOME PAGE | CODE PAGE | CZECH VERSION |
©  1998 - 2008 CZECH MEDICAL ASSOCIATION J. E. PURKYNĚ
Created by: NT Servis, s.r.o., hosted by P.E.S. consulting, s.r.o.
WEBMASTER