The need for improved cancer control led to the investigation of combined-modality therapy for many cancers. This review is an attempt of analysis of possibilities to apply simultaneously both treatment modalities in treatment of cancer diseases and shows the possible mechanism of interaction between chemotherapy and radiotherapy. Further in this review is showed benefits of this method combined therapy and strategies of using chemotherapy and radiotherapy to treat different cancers.

        Key words: Radiotherapy - Chemotherapy - Carcinoma - Radiochemotherapy