Monochorionic Twins after Sterility Treatment by
Methods of Assisted Reproduction
Hulvert J., Mardešič T., Müller P., Vobořil J., Miková M., Hüttelová R.,
Bečvářová V., Jirsová S.
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Summary:
Objective: The goal of this study has been to determine frequency of occurrence of monochorial
twins within the study group consisting of 521 pregnancies conceived through the In Vitro Fertili-
zation (IVF) programme.
Design: An observational study.
Setting: Sanatorium Pronatal, Na Dlouhé mezi 4/12, 147 00 Praha 4 - Hodkovičky.
Methods: A condition to be included in the study group was that there was a gestation sac detec-
ted by ultrasound. The first ultrasound examination was performed transvaginally and was done
between the fifth and the sixth week of each pregnancy. A multiple pregnancy has been classified
as monochorial in case when gestation sac contains two yolk sacs and two fetuses.
Results: Within the whole study group there were 13 monochorial twins which presents 2.5% of all
pregnancies. The incidence of monochorionicity among all multiple pregnancies is 6,4%, in IVF
cycles without micromanipulation techniques the occurence of monochorial twins has been 0.9%,
following cryoembryotransfer 3.9%, with micromanipulation (ICSI, AH) it reaches 5.7% of all
pregnancies.
Conclusion: Monochorial twins were detected seven time more frequent in comparison within
occurence in ordinary population. The occurence rises in connection with the number of fetuses
in uterus. In comparison with simple IVF cycles we have proved higher occurence of monochorio-
nicity in connection with micromanipulation techniques and cryoembryotransfer.
Key words:
monochorial twins, in vitro fertilization, micromanipulation techniques
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