Prognosis of patient in critical condition is influenced by quickness and effectiveness of solution of primary inzult. Nutrition support is an important part of therapy. Increasing interest has been focused on parenteral application of glutamine in the last years. Quickly growing tissues - enterocytes, blood cells, and immune systém cells - are main consumers of glutamine. Glutamine is anon esential aminoacid, which becomes conditionally essential during situations of hypercatabolism. We can expect a beneficial effectof its parenteral application in management of critical statě patients atintensivecare units

        Key words: multiorgan dysfunction, glutamine, parenteral nutrition support, immunity