Quality of Therapeutic Control of Hyperlipidemias in Secondary
Prevention of Coronary Heart Disease
Mayer O. Jr.1, Mayer O.Sr.2
1Centrum preventivní kardiologie II. interní kliniky Lékařské fakulty UK a FN, Plzeň, přednosta doc. MUDr. Jan Filipovský, 2Oddělení klinické farmakologie FN, Plzeň, přednosta doc. MUDr. Otto Mayer, CSc., Sr. |
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Summary:
Definite evidence has been established, that coronary patients benefit from appropriate therapeutic
control of risk profile, as recommended by several Guidelines. However, the impact of these
Guidelines on coronary morbidity and mortality is limited by level of its implementation into
broad clinical practice and possibility to reach the defined secondary preventive targets with
currently available therapeutic resources. We reviewed 6 studies, realized between 1995 and 2000,
which was aimed to establish, how many patients with clinical coronary heart disease achieved
recommended targets for lipid-lowering treatment. From 10850 cardiac patients examined in
these surveys, in average 42.8 % were treated with lipid lowering drugs, but only in 26.8 % and
24.3 % of patients was reached the target level for total and LDL cholesterol, resp. On the other
hand use of lipid lowering drugs markedly increased from about 16 - 32 % in 1995 61 - 93 % in 2000,
moreover in the same time period the proportion of patients reaching target levels of total cholesterol
increased from about 14 - 18 % to 30 - 64 %.
Key words:
Coronary heart disease - Secondary prevention - Hyperlipidemia - Treatment
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