Summary:
The author deals with side-effects of antidepressants in 498 out-patients treated in the Military
Hospital in Olomouc. The side-effects frequency of the antidepressants of the first generation was
40.6%, of the second generation 48.1%, of the third generation 22.4%, of the fourth generation
12.5% and of IMAO 34.7%. Occurrence of side-effects found in this study was compared to findings
in literature. In our sample the antidepressants with better tolerance were used more often than
medicaments with a higher occurrence of side-ffects. The antidepressants of the third generation and IMAO are becoming drugs of first choice for outatients.
Key words:
antidepressants, side-effects, tolerance,
out-patients.
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