The overview of analgosedation regimens used presently in the authors department is presented. The basic aspects of current opinion on this part of intensive care with possible risks and hazards are analysed. The ideal sedation regimen does not exist and it is important to emphasise that optimum dosage must be tailored to the individual’s response. Role of nurse is essential, especially in the time of weaning from analgosedation and mechanical ventilation. Very often problem in ICU is withdrawal syndrome. Weaning strategy is demonstrated. Cost effectiveness is one of the important factors observed in the field of intensive care at present. As well for that reason is morphin still used by intensivists.

        Key words: analgosedation – withdrawal syndrome – cost effectiveness