Summary:
In the study, 109 patients suffering from erectile dysfunction who were treated for 1–18 months
by moclobemid with a daily dose of 150–600 mg are kathamnestically evaluated. Their average
age was 49 y. (21–71 y.). The results of this treatment were always evaluated one month after
the preparation had been given, namely according to the ability of reaching the same level of
erection as before the inception of erectile dysfunction. The results is either „adjusted“ or „not
adjusted“ (i. e. the patient did/did not reach the level of erection as before the inception of erectile
dysfunction. 61% of the group (N=109) have been adjusted. A mostly psychogenically conditioned
erectile dysfunction was found in 60% of patients (N=65), a mostly organically conditioned one
in 40% (N=44). The infl uence of patients’ age on the length and result of treatment has turned
out to be statistically insignifi cant. In mostly psychogenically conditioned erectile dysfunctions
lasting 1–4 years, 74% of patients (N=40) were adjusted and also 55% (N=6) of those lasting 5–18
years. In mostly organically conditioned erectile dysfunctions lasting 1–4 years 58% (N=21) were
adjusted and 42% (N=15) were without effect. In mostly organically conditioned ones lasting 5–18
years no patient has been adjusted (N=8). If the treatment by moclobemid is successful, 90% of
these patients are adjusted in two months. Combination of moclobemid and yohimbine in the
watched group did not appear to be more successful than moclobemid monotherapy. That results
in the moclobemid treatment in erectile dysfunctions being indicated in: Psychogenical etiology
of the diffi culties, duration up to 4 years (even in case of organic etiology). It is recommended
for the treatment of unadjusted dysfunctions to continue if there are any signs of success of the
treatment in two months from the beginning of therapy.
Key words:
moclobemid, erectile dysfunctions.
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