CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. Stomat., roč. 108, 2008, č. 1, s. 9–13. |
Oral Mucositis as a Side
Effect of Myeloablative Chemotherapy in Hemato-oncological Patients Pink R.1, Pazdera J.1,Vondráková J.2, Faber E.2, Skoumalová I.2 1Klinika ústní, čelistní a obličejové chirurgie LF UP a FN, Olomouc, přednosta prof. MUDr. J. Pazdera, CSc. 2Hemato-onkologická klinika LF UP a FN, Olomouc, přednosta prof. MUDr. K. Indrák, DrSc. |
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Summary: The group of 20 patients treated for non-Hodgkin lymphomas and multiple myeloma was examined
by stomatologists before planned autologous transplantation of stem cells. After tooth sanation and removal
of the sources of local irritation and potential foci of odontogenic focal infection the patients were observed in the
course of 4 to 5 weeks after transplantation for the occurrence of oral mucositis. Oral mucositis of 1st to 2nd degree
(according to NCI-CTC classification) became manifest in the course of hemato-oncological treatment in all patients
in relation to the type of chemotherapy. After successful termination of hemato-oncological treatment
a spontaneous disappearance of oral mucositis developed. Low seriousness of oral complications of hemato-oncological
therapy confirms the importance of careful stomatological preparation of the patient before planned autologous
transplantation.
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