Atrial Fibrillation
Špinar J.1, Vítovec J.2
1II. interní klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta doc. MUDr. Miroslav Souček, CSc. 2I. interní kardio-angiologická klinika MU a FN u sv. Anny, Brno, přednosta prof. MUDr. Jiří Vítovec, CSc. |
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Summary:
Atrial fibrilation is the most frequent arrhythmia, the occurrence increasing with age and associated
diseases. The incidence at the age below 60 years is markedly lower than one per cent,
whereas in persons above 80 years of age it exceeds six per cent. The occurrence in patients with
heart failure is from 10 % (NYHA II) up to 50 % (NYHA IV). Atrial fibrillation is classified into that
observed for the first time and permanent, respectively, while transient forms include paroxyzmal
and persistent atrial fibrillation. The diagnosis is based on ECG recording, while echocardiography
is most significant. The therapy includes two basic questions – anticoagulant or anti-aggregation
treatment and the control of rhythm or frequency. The anticoagulant therapy should be
introduced in all patients, where contraindications are not present, being necessary before every
cardioversion, provided atrial fibrillation lasts more than two days. In patients without any heart
disease and with a physiological echocardiogram it is possible to administer only anti-aggregation
treatment. Cardioversion (the control of rhythm) is recommended to all symptomatic patients,
in other cases and especially in older persons the control of frequency is safer and of more
advantage. Electrical cardioversion is more effective that a pharmacological treatment, the sinus
rhythm is preferably controlled by dofetilid, ibutilid, propafenon and amiodaron. For the control
of heart rate beta-blockers, diltiazem, verapamil and digitalis are recommended.
Key words:
Atrial fibrillation - Anticoagulant treatment of atrial fibrillation - Control of rhythm -
Control of frequency - Electrical cardioversion
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