Prior to treatment, we háve sampled blood from 60 patients suffering carcinoma of the larynx and pharynx. CD4 lymphocytes were separated from the blood. We háve followed up their capacity of surface adherence depending on the presence of antigen (leucocyte adherence inhibition assay). As antigen there served a spe-cific antigen prepared from the corresponding tumor tissue (mitochondrial antigen of the tumor cell) and a nonspecific antigen prepared from the sérum of inbred C3H/H2K strain mice infected with LDH virus (cap-sid antigen). The results were evaluated with the aid of the non-adherence index (NAI). The experiment was repeated under exposure of the substráte to a magnetic sinusoid field (MSF) of power frequency at an induc-tion of 1 and 10 mT. The results were evaluated in like manner and compared through the t-test for two inde¬pendent series. Results of the measurings showed that CD4 lymphocytes obtained from the blood of patients suffering carcinomas of the larynx and of the pharynx, as compared to CD4 lymphocytes of healthy subjects, háve a decreased capacity of surface adherence (higher NAI values). Upon exposure to MSF of power net¬work frequency their capacity to adhere increased to a statistically significant degree. On presumption that the adherence capacity of lymphocytes is a manifestation of cell-mediated immunity (CMI), it can be stated that MSF influences CMI in a positive sense, námely in the čase of MSF of power network frequency at an induction of 1 and 10 mT.

        Key words: carcinoma of the larynx and pharynx - magnetic sinusoid field - leucocyte adherence inhibition assay.