CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. a slov. Neurol. Neurochir., 69/102, 2006, No. 3, p. 189–194. |
Reliability
of Localizing Primary Motor Area Using Functional Magnetic Resonance Bartoš R.1, Jech R.2,3, Vymazal J.3, Cihlář F.4, Hejčl A.1, Sameš M.1 1 Neurochirurgické oddělení MN, Ústí nad Labem 2 Neurologická klinika 1. LF UK a VFN, Praha 2 Neurologická klinika 1. LF UK a VFN, Praha 3 Radiodiagnostické oddělení, Nemocnice Na Homolce, Praha 4 Radiodiagnostické oddělení MN, Ústí nad Labem |
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Summary: Functional magnetic resonance is a noninvasive method used for mapping cortical
functions. Within 2003–2005 we compared fMRI and electric cortical stimulation
results of primary motor area in 14 patients with tumors located in the central
motor area. During fMRI the primary sensorimotor area was activated by rhythmic
touching the thumb to the other fingers. The fMRI results were gained on the
significancy levels P<0.001 without correction and P<0.05 FWE corrected. Eight
patients (57 %) demonstrated good correlation of both function localizing methods.
In 3 patients (21.5 %) the equality was only partial, with finding one positive
motor response to cortical stimulation gained out of the BOLD signal. Three
patients (21.5 %) showed full mismatch of results of both methods. The sensitivity
of fMRI for localizing the brain cortex with a motor function was 63 %. Retrospective
evaluation of morphological MR scans has demonstrated that mismatch
of the results was probably caused by local depression of BOLD signal by
collateral oedema and/or infiltrative growth of the tumor.
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