Assessment of Human
Chorionic Gonadotrophin and Alpha-1-fetoprotein by IMMULITE and SEVAPHARMA
Kits in Maternal Serum of Pregnant Women in the First Trimester
Matouš-Malbohan I. 1 , Fialová L. 1 , Mikulíková L. 2 , Nekvasilová H. 3
1 1. ústav lékařské chemie a biochemie, 1. lékařská fakulta Univerzity Karlovy, Praha 2 Ústav klinické biochemie, 1. lékařská fakulta Univerzity Karlovy, Praha 3 BIOVENDOR spol. s r.o., Brno |
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Summary:
The aim of this study was to compare maternal serum levels of alpha-1-fetoprotein (MS AFP) and human
chorionic gonadotrophin (MS HCG) in the 10 th – 14 th week of pregnancy assessed by Sevatest kits (SEVAPHARMA,
Czech Republic) and IMMULITE kits (Diagnostic Product Corporation, United States). We found a high corre-
lation between the two tested methods in all weeks of pregnancy (p < 0.0001). The results of maternal serum AFP
and HCG estimation obtained by Sevatest kits and IMMULITE kits are comparable.
Key words:
prenatal screening, first trimester, alpha-1-fetoprotein (AFP), human chorionic gonadotrophin
(hCG), IMMULITE.
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