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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
| Journals - Article | |
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| Česky / Czech version | Prakt. Lék., 83, 2003, No. 12, p. 695-696. |
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Activated Factor VII as the Perioperative Guarrancy of Splenectomy for
Severe Form of Corticoresistant ITP HADAČOVÁ I.1, HOCH J.2 1Hematologické oddělení FN Motol, Praha, přednostka prim. MUDr. I. Hochová 2Chirurgická klinika 2. LF UK a FN Motol, Praha, přednosta doc. MUDr. J. Hoch, CSc. |
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Summary: The main treatment of idiopathic thrombocytopenic purpura (ITP) in adults is based on
long-term application of corticosteroids. The different treatment modalities including surgery
may appear necessary in patients with corticoresistant ITP.
Demonstrating the case of a 36 year-old man suffering from corticoresistant ITP and severe
thrombocytopenia the authors discuss contemporary treatment possibilities and call attention
to the preparation for splenectomy by means of activated factor VII.They used NovoSeven (Novo
Nordisk) after the preparation by concentrated thrombocytes had failed. Splenectomy went
problem free, the patient healted primarily and the amounts of thrombocytes became stabilised.
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