Summary:
The authors examined a group of patients with medium severe and severe sleep apnoea syndrome. They
assessed differences in characteristics of the sleep apnoea syndrome in patients suffering from the
disease alone or concurrently from essential hypertension, with the objective to identify possible
preference of either group for indication of treatment of the syndrome. They evaluated the effect of
treatment by permanent overpressure in the airways on different parameters. In the sleep laboratory
68 patients with the sleep apnoea syndrome were evaluated. They were divided into group A. sleep
apnoea syndrome without other complaints – 34 patients, and group B. sleep apnoea syndrome with
essential hypertension – 34 patients. Complete all-night polysomnography was recorded, the day-time
activity was evaluated according to the Stanford scale of somnolence. For evaluation non-parametric
tests: Mann-Whitney U-Wilcoxon Rank Sum W test and Wilcoxon Matched – Pairs Signed Ranks Test
were used. No differences were revealed in the fundamental parameters characterizing the sleep
apnoea syndrome between patients suffering from the sleep apnoea syndrome alone and patients
suffering at the same time from essential hypertension and therefore there was no evidence for
preference of either group for indication of therapy with permanent overpressure. The differences in
the ratio of different stages of sleep are statistically significant, but insignificant from the functional
aspect. Treatment by permanent overpressure in the course of 12 months improved the quality of life
by improving day-time activity and the quality of sleep.
Key words:
sleep apnoea syndrome, permanent overpressure, CPAP, hypertension polysomnography
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