Treatment Outcomes of Colon Cancer Surgery Combined
With Radical Lymphadenectomy
Lipská L., Visokai V., Mráček M., Levý M.
Chirurgická klinika 1. LF UK a Fakultní Thomayerovy nemocnice s poliklinikou, Praha, přednosta: doc. MUDr. V. Visokai, Ph.D. |
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Summary:
The authors analyzed a group of 1281 subjects with colorectal cancer operated and followed up in a single institution from I/1992
to VIII/2007. Colon carcinoma patients were assessed separately (C18). Patients with rectal and rectosigmoid tumors are not included
in the presentation. A total of 846 patients were operated for colon carcinomas. In 546 subjects, radical R0 resections were achieved.
In the R0 group, the male/female ratio is 315/231, age 29–94 years, the mean age of 69 years. The R0 group stratification by
TNM classification was: I 17.8%, II 49.6%, III 24.0%, IV 8.1%, TNMx 0.5%. Irrespective of the TNM staging, three- year, five-year
and ten-year survival rates were 80%, 71%, and 51%, resp. The median survival time was 9.85 years. Postoperative morality was
5.5%, morbidity 29.8%, anastomic leak occured in 5.7%. Systematic lymph node dissection up to the apical level, had been gradually
introduced as an integral part of the R0 surgery. The aim of the study is to analyze outcomes of the colon carcinoma surgical management,
combined with radical lymphadenectomy. Furthermore, effects of the extensive procedure on the postoperative morbidity
and moratility rates are analyzed as well.
Key words:
colorectal cancer – colon cancer – surgical management – lymphadenectomy – radicality – R0 resection – survival – morbidity
– mortality
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