SPECTRAL COHERENCE BETWEEN
BLOOD PRESSURE AND INTER-BEAT
INTERVALS IN HYPERTENSION
Danev S. 1 , Datzov E. 1 , Svetoslavov S. 2 , Mikhov D. 3 , Markova P. 3 , Girchev R. 3
National Centre of Hygiene, Medical Ecology and Nutrition, Sofia
2 Technical University, Sofia
3 Medical University, Sofia, Bulgaria |
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Summary:
Continuous registration of blood pressure (BP) was obtained in 31 normotensives and 76 hypertensives (divided into 3 stages of
hypertension) by a method where the blood pressure in a human finger was measured non-invasively in a beat-by-beat fully calibrated
manner. From this signal, the power density spectra of inter-beat intervals (IBI), systolic blood pressure (SBP) and diastolic blood pressure
(DBP) were derived. Total spectral power (TP) and low/high spectral frequency ratios of all spectra were calculated. Cross-correlation
analysis between IBI, SBP and DBP spectra showed that the level of amplitude and phase spectral coherence (SC) was strongly dependent
of the stage of hypertension. SC was calculated by means of appropriate mathematical algorithms. Multiple step regression analysis pointed
out that the observed phenomenon is highly significant for both – the amplitude and the phase SC (p<0.01).
Key words:
heart rate variability, blood pressure, power spectrum, cross-spectrum
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