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  Česky / Czech version Rozhl. Chir., 2004, roč. 83, č. 11, s. 579-585.
 
The Influence of Chloroquine to Some Biochemical and Hematological Parameters in Patients with Critical Limb Ischemia 
Mondek P., Slyško R., Šefránek V., Pecháň I.1 

Klinika cievnej chirurgie, Slovenský ústav srdcových a cievnych chorôb, Bratislava, Slovenská republika, prednosta prof. MUDr. V. Šefránek, CSc. 1 Oddelenie klinickej biochémie, SÚSCH, Bratislava, Slovenská republika
 


Summary:

       CLI represents a majormedical and social problem. The incidence is increasing and currently it was estimated 500–1000 per 1 million inhabitants. We carried out a clinical study (2000–2004) concerning monitoring of some hematological and biochemical markers during reperfusion in patients with CLI. The subject of our interest included possibilities to influence PMNL elastase by medical means and neutrophil-lymphocyte ratio which is considered a reliable and simple parameter to assess severity of clinical conditions.

        Key words: ischemia – reperfusion – PMNL elastase – neutrophil-lymphocyte ratio
       

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