Summary:
The authors present an account on syndromes caused by extraarticular inflammatory changes of
the blood vessels in rheumatoid arthritis (RA). The most serious one among them is systemic
rheumatoid vasculitis. It threatens the subset of RA with a defined predisposition. The main
manifestations comprise fatigue, loss of body weight, dermal changes (incl. acral isch aemia) and
mononeuritis multiplex. The diagnosis is supported by bioptic evidence of fibrinoid necrosis in the
active stage of the disease. Early intensive therapy (the basis is IV pulsed cyclophosphamide
treatment) improves the prognosis quoad vitam and reduces the risk of relapses. The review includes
basic information on leukocytoclastic vasculitis in RA, rheumatoid aortitis and digital vasculitis in
RA.
Key words:
rheumatoid arthritis, systemic rheumatoid vasculitis, leucocytoclastic vasculitis,
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