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  Česky / Czech version Čas. Lék. čes., 2006, 145, pp. 688–694.
 
Biological Mechanisms of Aging 
1Otová B., 2Kalvach Z., 2Šnejdrlová M. 

1Ústav biologie a lékařské genetiky 1. LF UK a VFN, Praha 2III. interní klinika 1. LF UK a VFN, Praha
 


Summary:

       Contemporary views on the mechanisms of aging and aging variations – progeria and longevity are presented. Replicative aging, the roles of glycation and free radicals on the genetical determination of progeria and longevity are discussed.

        Key words: aging, senescence, involution, progeria, longevity.
       

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