Carcinoma of the Meibomian gland of the eyelid is very rare with atypical glandular features, that may appear initially as a chalazion formation and then invades the neighbouring tissues. PURPOSE: Demonstration of the importance of surgical excision and histological examination in presence of an apparently harmless tumoral alteration of the eyelids and verifiyng every case of atypical lesion of the eyelid region. Case presentation No. 1: We report a case of 76-year old woman patient suffering from chronical blepharoconjunctivitisandchronical chalazionmanytimes simply performed excochleation. Histopathological finding of the excision of the tumour showedthepresence of carcinomaMeibomiangland(stageG2),the patient refused exenteration and died in 2 month interval. Case presentation No. 2.: 65-year old men with carcinoma linguae 1.sin. (T3 N2 M0) in 1998 after hemiglossectomia, resectionem baseos oris 1.sin. and radiotherapy, came to our clinic with exoftalm and tumor in his right orbit in Jun 2001. CT found tumour 3x2x2cm. In September 2001 orbitotomia bicoronalis 1.sin., extirpatio TU orbitae 1.sin. histologically verified karcinoma of Meibomain gland, patient without any problems after operation and radiotherapy.

        Key words: Carcinoma, Meibomian gland