CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čs. Patol., 38, 2002, No. 2, p. 83-88 |
Post-fine-needle Aspiration Cytology Changes of Thyroid Gland Ryška A., Ludví`ková M., Kholová L, Čáp J 3 Fingerlandův ústav patologie, Lékařská fakulta UK a Fakultní nemocnice, Hradec Králové Šiklův patologicko-anatomický ústav, Fakultní nemocnice, Plzeň II. interní klinika, Lékařská fakulta UK a Fakultní nemocnice, Hradec Králové |
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Summary: Due to the introduction of fine needle aspiration cytology (FNAC) to the routine clinical preoperative egamination surgical pathologists are faced with thyroid gland specimens with FNAC-induced secondary changes. These changes can cause diagnostic difficulties and be a Bource of incorrect diagnosis. Authors present a review of FNAC-induced changes with differential diagnostic criteria helpful in these pitfalls. FNAC-induced changes can be schematically divided finto two major groups - recent ones (intranodal bleeding and/or necrosis) and subacute/late ones (proliferation of granulation tissue with predominance of myofibroblasts or endothelial cells, resorptive pseudogantomathous granulomas, formation of sarcoid-like granulomas, capsular pseudoinvasion and scarring).
Pathologists should be informed about the previously performed FNAC and must be aware of these lesions to prevent their misinterpretation.
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