Morykwas and Argenta developed Vacuum Assisted Closure (VAC®) in the early 90s for the treatment of tissue defects. In 2004, for the first time at our workplace, we used this method in the treatment of six patients between 54 and 91 years of age. Two of the patients were treated for a varicose ulcer on a lower extremity, two patients for loss of skin after an inflammation secondary to infection, one high-risk patient for deep burns, and one patient for a deep defect caused by an inappropriate medical care.We observed blood circulation improvement in all patients, which permitted an early dermo-epidermal graft.

        Key words: wound healing, subatmospheric pressure, granulation, infection, economic gain