Summary:
Phylloides tumor of the breast is well known entity in pathology for a long time. It includes
fibroepithelial tumors of the different biological character. They are generally divided into three
groups: benign, low-grade malignant (borderline) and high-grade malignant. Adenoses of the
breast are a group of the benign lesions, the main feature of which is the proliferation of the
glandular component of the breast. More frequent adenoses occurring in practice are: blunt duct
adenosis, sclerosing adenosis, nodular adenosis, adenosis tumor and florid adenosis. The less
frequent adenoses are: microglandular adenosis, tubular adenosis, apocrine adenosis, and myoepithelial
(adenomyoepithelial) adenosis. In this article two histologically unusual lesions of the
breast in middle-aged women are presented, consisting of the benign variants of the phylloides
tumor, modified distinctly by various types of adenoses, which can cause, together with intensive
myoepithelial proliferation, great diagnostic problems, especially on frozen sections. They may be
mistaken with invasive ductal or lobular cancer. Reliable differentiation between these entities is
possible only by using of the immunohistochemical methods.
Key words:
benign phylloides tumor of the breast - adenosis of the breast - myoepithelial proliferation
- invasive carcinoma - frozen section - immunohistochemistry
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