Summary:
The author summarises the reasons why the depressive disorder and its treatment is so important
and she shows the list of new antidepressants. The variables associated with the choice of antidepressants
are divided into variables connected with the drug (efficacy, tolerability, safety) and
variables connected with the patient. There are included age and sex of patient, symptoms,
subtypes of depression, comorbidity with psychic and somatic disorder. In the near future the
genetic information will also be used. It is necessary for the good choice of antidepressant for the
right patient to have knowledge about antidepressants that are available and to assess carefully
the psychic state including dynamic of the disorder and pharmacological history.
Key words:
choice of antidepressant, efficacy, tolerability, safety, age, sex, subtypes of depression,
comorbidity.
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