Summary:
Stenosing tumours of the terminal common bile duct are included amongst those neoplasms with the worst
prognosis. Due to limitations of radical surgical therapy, along with a relatively short period of survival, some
authors hase consequently rejected surgical therapy in favour of palliative endoscopic drainage of the bile
ducts.
Materials and Methods: (Between 1995 and 2003), surgery was performed in our clinic of 129 patients for
stenosing tumours of the common bile duct. We evaluated tumour histology, perioperative mortality, morbidity
after both radical and palliative surgery, as well as long term results of therapy assessed using median time of
survival for the individual tumour types. Recurrence of common bile duct obstruction postoperatively was also
evaluated.
Results: Ductal adenocarcinoma of the pancreas was the cause of terminal bile duct obstruction in the
majority of cases. Different tumour histology was found however in more than 40% of the tumours that were
able to be resected. A 5% mortality rate within 30 days was found; the morbidity rate was 19%. The median
rate of survival after radical surgery was 17.5 months, as compared with 5.5 months in patients following
palliative procedures. Obstructive jaundice recurred in 3% of patients.
Conclusion: In comparing our results with those after published endoscopic palliative measures, it is evidence
that both procedures are comparably effective in palliative treatment of the bile duct tumours, providing
correct indication. Surgery is furthermore preferred in potentially resectable tumours, and in younger patients
with perspective of longer survival.
Key words:
choledochus stenosis – carcinoma of pancreas – icterus – radical resection – palliative treatment
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