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  Česky / Czech version Čes. Revmatol., 9, 2001, No. 3, p. 103-109
 
Inaccuracies in Bone Densitometry for T-score Values (Comparative Study) 
Wendlová J. 

Osteologická ambulancia FNsP ak. L. Dérera, Bratislava
 


Summary:

       The authors examined 56 postmenopausal women aged 43 to 68 years and 28 men aged 40 to 66 years suffering from osteopenia or osteoporosis, according to the WHO classification. In every patient the following measurements were made: A) T-score for: 1) the index of stiffness (S) of the left heel, USM, 2) the bone mineral density of the left heel (BMDp), DEXA (g Ca hydroxyapatite/cm2), 3) the bone mineral density of the trabecular vertebral bone L1 (BMDL 1), QCT (mg Ca hydroxyapatite/cm3), B) Z-score for 1) S of the left heel bone, USM (index) 2) BMDp of the left heel bone, DEXA (g Ca hydroxyapatite/cm 2 only in the group of women, for men the apparatus did not give values of the Z-score, 3) BMDL 1 of the trabecular bone of the vertebra L1 QCT (mg Ca hydroxyapatite/cm2. Objective: To determine the character of the distribution of values of T-score and Z-score for the selected measurements and compare them using statistical analysis. Statistical analysis: The differences among the assessed values of T-score (Z-score) were evaluated by the parametric or non-parametric method of determining of 95% confidence intervals (CI). Results: The differences between values of the Z-score and between the T-score were statistically significant, whereby the differences were lower in values of Z-score in both groups. Conclusion: The greatest differences between 95% CI characterizing individual measurements of T-score values (as compared with Z-score) were found in those densitometers whose ageefined reference groups of young adults differed most and conversely, the smallest differences were found between age-defined reference groups. In the higher variation of values of the T-score and Z-score participates the non-standard selection of a reference group of young adults for densitometers QCT, PIXI, Achilles plus used in the study. The age characteristic of a reference group for the T-score should be a standard one for all types of densitometers.

        Key words: bone densitometric methods, T-score, Z-score, diagnostics of osteoporosis
       

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