The Risk of Malignancy After Organ Transplantation
1, 2Gürlich R., 3Novotný J., 4Stříž I., 5Honsová E., 1Oliverius M., 1Janoušek L., 6Pokorná E., 7Maruna P.
1Klinika transplantační chirurgie IKEM, Praha 2I. chirurgická klinika 1. LF UK a VFN, Praha 3Onkologická klinika 1. LF UK a VFN, Praha 4Oddělení klinické imunologie1. LF UK a VFN, Praha 5Pracoviště klinické a transplantační patologie1. LF UK a VFN, Praha 6Transplantcentrum IKEM, Praha 7Ústav patologické fyziologie 1. LF UK, Praha |
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Summary:
Improvements in immunosuppressive therapy during the past decade brought about improvements of the long term
tolerance of organ allografts. However, the long-term immunosuppressive therapy has an important limitation,
because it can increase the risk of cardivascular diseases, infections and tumors. As compared with age-matched
healthy population, organ-transplant recipients have an increased incidence of tumors.
Key words:
immunosuppression, tumor, transplantation.
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