Summary:
Renal anaemia causes in patients with chronic renal failure numerous serious problems which can be favourably
influenced by improvement of the anaemia. There is a number of known factors which cause deterioration of anaemia
and make its treatment more difficult. For a long time it was not clear that these negatively acting factors included
also insufficiently effective dialysis treatment. The authors of the submitted paper evaluate the relationship between
anaemia and the effectiveness of dialysis based on new data reported in the literature and their own results. From
this evaluation ensues that inadequate haemodialysis, assessed from the percentage reduction of urea in blood, is
associated with a reduced response to recombinant human erythropoietin which is the basic remedy of renal anaemia.
If the inadequate intensity of haemodialysis is increased, anaemia improves substantially. In patients on continuous
ambulatory peritoneal dialysis (CAPD) there is a direct relationship between the effectiveness of blood purification
expressed by the index KT/Vurea, i.e. the indicator of urea elimination, and the severity of anaemia. In patients treated
by CAPD there is a significant association between the haematocrit and KT/Vurea supplied by the peritoneum as well
as the kidneys. KT/Vurea supplied by the patient’s own kidneys is from the aspect of anaemia more significant. Some
facts regarding the relationship between anaemia and the effectiveness of dialysis treatment remain obscure so far.
This however does not influence the fact that based on data available at present, effective dialysis must be included
among basic prerequisites of effective treatment of renal anaemia in dialyzed patients.
Key words:
chronic renal failure, renal anaemia, haemodialysis, peritoneal dialysis, effectiveness, adequacy,
erythropoietin.
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