Summary: Thin films of hydroxylapatite, about 500 nm, were formed on titanium alloy samples by excimer laser ablation Ten different deposition conditions were used such as deposition atmosphere (vacuum, pure water vapours, mixture of Ar and water vapours), substrate temperature, target-substrate distance and energy density. Mechanical and physical analyses were carried out by Rutherford backscattering, Particle Induced X-Ray Emission, crystallinity of films by x-ray diffraction, surface morphology by Scanning Electron Microscopy and adhesion by a scratch test. Biological evaluation of samples was also performed. The fibroblast proliferation test, morphological evaluation of macrophages and activity of lympho- cytes cultured in the presence of implants were implemented.

        Key words: dental implants – hydroxylapatite – titanium – fibroblasts