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  Česky / Czech version Čas. Lék. čes., 139, 2000, No. 24, p. 767-771
 
New Possibilities of Surgical Treatment of Males After Non-Successful Operation for the Urethral Strictures Relapses 
Šimon V., Vacík J., Michálek J., Novák V., Lopour P., Špunda M. 

Urologická klinika 1. LF UK a VFN, Praha Ústav makromolekulární chemie AV ČR, Praha Vysoká škola chemicko-technologická, Praha Ústav biofyziky 1. LF UK, Praha
 


Summary:

       Background. Subvesical obstruction of any origin represent a frequent and serious disorder occurring predominantly in males. Often it brings incontinence and/or erectility dysfunction, infection of urinary tract. Relapses of the acute pyelonephritis can turn into chronic tubulointersticial one and terminate in the renal insufficienty. To treat strictures, dilation, intermittent catheterization and recently stent introduction were used. Most suitable appears a stent from composite polymers. The aim of our work was to test properties of stents developed in the Institute of Macromolecular Chemistry ASCR. Methods and Results. Stents from composite polymers, which are non-toxic, not-irritable can swell in body fluids and have mechanical properties similar to that of silicone rubber. Properties of the material are functionally graded and the casting or repoussé from the material can subsequently change its shape. Ten patients (males, aged 25 to 78 years) with long urethral strictures in its bulbocavernous part (50 %) were treated with this method. Strictures were caused by pelvical fractures (4 times), prostate hypertrophy surgery (4 times), prolonged catheterizations (2 times). All patients were followed for 16 to 26 month and had no severities. Conclusion. Our results indicate that stent from composite polymers and silicone may have long-acting effects without irritation or crust formation and beneficially effected healing of the spongio-fibrous process.

        Key words: relapses of urethral strictures, intermittent catheterization, stent, hydrofile polysiloxane rubber, polymers, vulcanised replacements.
       

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