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  Česky / Czech version Čes. Stomat., roč. 107, 2007, č. 2, s. 29-31.
 
II. Titanium Modified with Hydroxyapatite and Zirconium - Biological Properties 
Seydlová M.1, Teuberová Z.2, Dostálová T.1, Dvořáková B.3, Smetana K. Jr.3, Jelínek M.4, Mašinová P.4, Kocourek T.4, Kolářová K.5, Wilson J.6 

dětská stomatologická klinika 2. LF UK a FN Motol, Praha 2Protetické oddělení, Stomatologická klinika 1. LF UK a VFN, Praha 3Anatomický ústav 1. LF UK, Praha 4Fyzikální ústav AV ČR, Praha 5Ústav chemických technologií VŠCHT, Praha 6Fakulta nukleárních věd a fyzikálního inženýrství, Česká technická univerzita, Praha
 


Summary:

       Summary: Coated implants representing one of modern trends in implantology háve been the subject of our investigation. After detailed technical tests of three different types of samples — titanium alloy TiAlgV4, titanium alloy covered with zirconium and titanium alloy covered with hydroxyapatite with a zirconium interlayer, the authors tested proliferation and metabolic activity of human embryonic lung fibroblasts in the neighborhood of the samples. In the Burker chamber the authors calculated the harvested cells and performed the MTT test. It has become obvious that the sample was not cytotoxic and the surface of the samples made cellular colonization possible. Pulse laser deposition appears to be a promising method in the area of coating the implants on the metal core and biological tests indicate that the coating from crystalline hydroxyapatite may improve biological properties of titanium coated with hydroxyapatite with an interlayer of zirconium.

        Key words: dental implant - laser ablation - crystalline structure - cellular proliferation - MTT test
       

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