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  Česky / Czech version Čas. Lék. čes., 141, 2002, No. 22, p. 715–717.
 
Cutaneous Complications of the Idiopathic Inflammatory Bowel Disease 
Chalupná P., Lukáš M., Adamec S., Šroubková R., Antošová M., Romaniv S. 

Gastroenterologické centrum IV. interní kliniky 1. LF UK a VFN, Praha
 


Summary:

       A 29-year-old male patient with the anamnesis of inflammatory bowel disease and Grave-Basedowov disease was hospitalized because of rapidly spreading skin defect with affected muscle on the left shin. This skin defect appeared after the significant decreasing of corticoids. The small skin trauma preceded the pyoderma gangrenosum. First the skin diseasewas not right diagnosed and patient was cured by the excision of the defect. It caused tissue disintegration, muscle necrosis and extension of the defect. The whole leg was endangered. Patient was cured with corticoids and cyclosporin A after the right diagnosis. The defect healed and laboratory inflammatory markers decreased. The immunosupresive therapy was changed to azathioprin, the corticoid therapy was interrupted. After three months the defect was healed.

        Key words: inflammatory bowel disease – pyoderma gangrenosum – cyclosporin A.
       

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